Synonyms for achalasia or Related words with achalasia

anismus              dysmotility              varices              haemorrhoids              proctalgia              diverticulitis              dyssynergia              dysphagia              diverticulosis              cricopharyngeal              sclerodactyly              diverticular              paraphimosis              colics              varicies              pseudoobstruction              oesophageal              oddi              sialadenitis              achlorhydria              phimosis              odynophagia              dysphasia              vigoruos              hemorrhoids              dysuria              laryngopharyngeal              vesicoureteral              atony              cerebellaris              myoclonica              haemorrhoidal              colic              epistaxis              extraesophageal              odontomatosis              ankyloglossia              sialolithiasis              anorectal              rhagades              omphalocele              oesophagitis              sclerodactyl              cholecystitis              dismotility              adenitis              oesophagus              spasm              indigestion              cholangiopathy             

Examples of "achalasia"
Achalasia (; "a-" + "-chalasia" "no relaxation") is a failure of smooth muscle fibers to relax, which can cause a sphincter to remain closed and fail to open when needed. Without a modifier, "achalasia" usually refers to achalasia of the esophagus, which is also called esophageal achalasia, achalasia cardiae, cardiospasm, and esophageal aperistalsis. Achalasia can happen at various points along the gastrointestinal tract; achalasia of the rectum, for instance, in Hirschsprung's disease.
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Patients with idiopathic achalasia show a significant difference in the distribution of SNPs affecting VIPR1.
The failure of the lower esophagous sphincter to respond properly to swallowing is called achalasia.
Achalasia is an idiopathic motility disorder characterized by failure of lower esophageal sphincter (LES) relaxation as well as loss of peristalsis in the distal esophagus, which is mostly smooth muscle. Both of these features impair the ability of the esophagus to empty contents into the stomach. Patients usually complain of dysphagia to both solids and liquids. Dysphagia to liquids, in particular, is a characteristic of achalasia. Other symptoms of achalasia include regurgitation, night coughing, chest pain, weight loss, and heartburn. The combination of achalasia, adrenal insufficiency, and alacrima (lack of tear production) in children is known as the triple A (Allgrove) syndrome. In most cases the cause is unknown (idiopathic), but in some regions of the world, achalasia can also be caused by Chagas disease due to infection by "Trypanosoma cruzi".
Though this surgery does not correct the underlying cause and does not completely eliminate achalasia symptoms, the vast majority of patients find that the surgery greatly improves their ability to eat and drink. It is considered the definitive treatment for achalasia.
Achalasia is a major exception to usual pattern of dysphagia in that swallowing of fluid tends to cause more difficulty than swallowing solids. In achalasia, there is idiopathic destruction of parasympathetic ganglia of the Auerbach's (Myenteric) plexus of the entire esophagus, which results in functional narrowing of the lower esophagus, and peristaltic failure throughout its length.
The cause of most cases of achalasia is unknown. LES pressure and relaxation are regulated by excitatory (e.g., acetylcholine, substance P) and inhibitory (e.g., nitric oxide, vasoactive intestinal peptide) neurotransmitters. People with achalasia lack nonadrenergic, noncholinergic, inhibitory ganglion cells, causing an imbalance in excitatory and inhibitory neurotransmission. The result is a hypertensive nonrelaxed esophageal sphincter.
In human pathology a condition known as achalasia may predispose a person to slowly develop megaesophagus. Achalasia is due to the loss of ganglion cells of the myenteric plexus. It occurs mostly in middle aged adults. There is a marked lack of contraction within the muscles involved in peristalsis with a constant contraction of the lower esophageal sphincter. Dilation of the esophagus results in difficulty swallowing. Retention of food bolus is also noted. Chagas disease is one cause of megaesophagus in humans. Achalasia also predisposes to esophageal carcinoma.
Achalasia is a motor disorder of the esophagus characterized by decrease in ganglion cell density in the myenteric plexus. The cause of the lesion is unknown.
Due to the similarity of symptoms, achalasia can be mistaken for more common disorders such as gastroesophageal reflux disease (GERD), hiatus hernia, and even psychosomatic disorders.
Incidence of achalasia has risen to approximately 1.6 per 100,000 in some populations. Disease affects mostly adults between ages 30s and 50s.
In a Nissen fundoplication, also called a complete fundoplication, the fundus is wrapped the entire 360 degrees around the esophagus. In contrast, surgery for achalasia is generally accompanied by either a "Dor" or "Toupet" partial fundoplication, which is less likely than a Nissen wrap to aggravate the dysphagia that characterizes achalasia. In a Dor (anterior) fundoplication, the fundus is laid over the top of the esophagus; while in a Toupet (posterior) fundoplication, the fundus is wrapped around the back of the esophagus.
The most common form is primary achalasia, which has no known underlying cause. It is due to the failure of distal esophageal inhibitory neurons. However, a small proportion occurs secondary to other conditions, such as esophageal cancer or Chagas disease (an infectious disease common in South America). Achalasia affects about one person in 100,000 per year. There is no gender predominance for the occurrence of disease.
Triple-A syndrome (AAA), also known as Achalasia-Addisonianism-Alacrima syndrome or Allgrove syndrome, is a rare autosomal recessive congenital disorder. In most cases, there is no family history of it. The syndrome was discovered by Jeremy Allgrove and colleagues in 1978. Triple A stands for achalasia-addisonianism-alacrima syndrome. Alacrima is usually the earliest manifestation. It is a progressive disorder that can take years to develop the full blown clinical picture.
Autopsy and myotomy specimens have, on histological examination, shown an inflammatory response consisting of CD3/CD8-positive cytotoxic T lymphocytes, variable numbers of eosinophils and mast cells, loss of ganglion cells, and neurofibrosis; these events appear to occur early in achalasia. Thus, it seems there is an autoimmune context to achalasia, most likely caused by viral triggers. Other studies suggest hereditary, neurodegenerative, genetic and infective contributions.
The per-oral endoscopic myotomy, or POEM, is a surgical procedure for the treatment of achalasia wherein the inner circular layer of the lower esophageal sphincter is divided through a submucosal tunnel[]. This enables food and liquids to pass into the stomach a process that is impaired in achalasia. The tunnel is created, and the myotomy performed, using a flexible [endoscope]], meaning the entire procedure can be done without external incisions.
Cricopharyngeal myotomy is a surgical sectioning of the cricopharyngeus muscle, also known as the upper esophageal sphincter, that has been advocated for the treatment of cricopharyngeal spasm, or cricopharyngeal achalasia, that leads to cervical dysphagia in the clinical setting.
This is a somewhat challenging operation, and surgeons have reported improved outcomes after their first 50 patients. An author search at Google Scholar can be used to find studies on a surgeon's past experience with achalasia patients.
2) Solid plus liquid dysphagia is due to Esophageal motility disorder (or dysmotility) either upper esophagus (Mysthenia Gravis, stoke, or Dermatomyositis) or Lower esophagus (systemic sclerosis, CREST syndrome, or Achalasia)