Synonyms for acromegaly or Related words with acromegaly
Examples of "acromegaly"
His distinctive facial features were a result of
With Édouard Brissaud (1852–1909) he researched skeletal changes in
, concluding that gigantism in adolescents is fundamentally the same disease as
in adults. During World War I he conducted studies of neuropathy with Pierre Marie (1853–1940).
The 1858 image of Pio Pico was used as an example of florid
in the scientific review paper "
Pathogenesis and Treatment" published in " The Journal of Clinical Investigation."
A duplication event in "GPR101" is implicated in cases of gigantism and
Rana suffers from
, which, among other effects, causes gigantism and chin protrusion.
In a general sense, the suffix "-megaly" is used to indicate a growth, as in hepatomegaly,
, and splenomegaly.
The primary current medical treatment of
is to use somatostatin analogues – octreotide (Sandostatin) or lanreotide (Somatuline).
is an alternative diagnosis. From photographs of Rachmaninov in the 1920s and his portrait by Konstantin Somov in 1925 (Figure 1), at a time when he was recording his four piano concerti, the coarse facial features of
are not immediately apparent. However, a case can be made from later photographs...
He distinguished himself in research of hyperparathyroidism,
, Paget’s disease and pituitary gland abnormalities. His name is associated with "Erdheim's syndrome", a condition that is also known as "Scaglietti-Dagnini syndrome" (cervical spondylosis secondary to
). Other eponyms associated with him are:
Growth hormone receptor antagonists such as pegvisomant (trade name "Somavert") are used in the treatment of
. They are used if the tumor of the pituitary gland causing the
cannot be controlled with surgery or radiation, and the use of somatostatin analogues is unsuccessful. Pegvisomant is delivered as a powder that is mixed with water and injected under the skin.
Upon successful treatment, symptoms and complications generally improve substantially or disappear, including headaches, visual disturbances, excess sweating, and diabetes. Soft-tissue swellings generally decrease and
-associated facial features gradually return towards normal, although this may take some time. Life expectancy after the successful treatment of early
is equal to that of the normal population.
In a few patients,
is caused not by pituitary tumors, but by tumors of the pancreas, lungs, and adrenal glands. These tumors also lead to an excess of GH, either because they produce GH themselves or, more frequently, because they produce GHRH (growth hormone releasing hormone), the hormone that stimulates the pituitary to make GH. In these patients, the excess GHRH can be measured in the blood and establishes that the cause of the
is not due to a pituitary defect. When these nonpituitary tumors are surgically removed, GH levels fall and the symptoms of
The primary cause of an enlarged mandible is developmental or congenital. There are some rare disorders that can further widen the jaw such as
Pasireotide LAR was approved by the FDA for treatment of
in December 2014, and had been approved for this indication by the EMEA one month earlier.
He had wanted to become a lawyer, but his
prevented him from doing so. Tillet served in the French Navy for five years as an engineer.
is suspected, medical imaging and medical laboratory investigations are generally used together to confirm or rule out the presence of this condition.
Mary Ann Bevan (20 December 1874 – 26 December 1933) was an English woman who, after developing
, toured the sideshow circuit as "the ugliest woman in the world."
Side effects for peptide hormones and analogues are
(overgrowth of hands, feet, and some facial features), enlarged organs, and cardiovascular problems.
In Tampa, Hatton worked as a sportswriter for "The Tampa Tribune". He continued working as a journalist until after World War I, when the symptoms of
He was often compared with Sun Mingming, because both of them have
, and could slam dunk without their feet leaving the ground.
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