Synonyms for asthenozoospermia or Related words with asthenozoospermia
Examples of "asthenozoospermia"
(or asthenospermia) is the medical term for reduced sperm motility. Complete
, that is, 100% immotile spermatozoa in the ejaculate, is reported at a frequency of 1 of 5000 men. Causes of complete
include metabolic deficiencies, ultrastructural abnormalities of the sperm flagellum (see Primary ciliary dyskinesia) and necrozoospermia.
It decreases the sperm quality and is therefore one of the major causes of infertility or reduced fertility in men. A method to increase the chance of pregnancy is ICSI. The percentage of viable spermatozoa in complete
varies between 0 and 100%.
Certain medical studies had shown mitochondrial Haplogroup T to be associated with reduced sperm motility in males, although these results have been challenged . According to the Departamento de Bioquimica y Biologica Molecular y Celular, Universidad de Zaragoza, Haplogroup T can predispose to
. However, these findings have been disputed due to a small sample size in the study .
Males are more susceptible to mtDNA defects, not only because of lack of selection for mtDNA on males but also due to sperm’s higher energy requirements for motility. There are evidence showing mtDNA mutations are more likely to affect males. In humans, Leber's hereditary optic neuropathy (LHON) is caused by one or several point mutations on mtDNA and LHON affects more males than females. In mice, a deletion on mtDNA causes oligospermia and
, resulting in infertility. Taken together, mtDNA mutations pose a greater threat on males than on females.
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