SynonymsBot
Synonyms for hibm or Related words with hibm
apbd
chagasic
edmd
fshd
fxtas
homocysteinemia
patientsand
igan
ibmpfd
sibm
nonfamilial
cadasil
hefh
thalassaemia
thalassemic
thalassaemic
xlh
fsgs
hivan
ftld
xlhed
arvc
hypocholesterolemia
sojia
adhr
arpkd
progeroid
polyglucosan
eskd
mpgnii
ipah
atransferrinemia
sclerosteosis
lipodystrophic
hyperlysinemia
hlhs
progeria
nondemented
nonfh
lafora
musculardystrophy
otcd
fructosuria
hadds
aatd
xlmtm
alports
bfie
herda
nephronophthisis
Examples of "hibm"
Inclusion body myositis (IBM) is an inflammatory muscle disease characterized by slowly progressive weakness and wasting of both distal and proximal muscles, most apparent in the muscles of the arms and legs. There are two types: sporadic inclusion body myositis (sIBM), which is more common, and hereditary inclusion body myopathy (
hIBM
).
The disease GNE myopathy [formerly known as hereditary Inclusion Body Myopathy (
HIBM
), and Distal Myopathy with Rimmed Vacuoles (DMRV)] is manifested as progressive muscle weakness. GNE myopathy is a rare genetic disorder caused by hyposialylated muscle proteins and glycosphingolipids because there is insufficient metabolic ManNAc to form the Neu5Ac terminal sugar. There is no available therapy to treat GNE myopathy.
Hereditary inclusion body myopathies (
HIBM
) are a heterogeneous group of very rare genetic disorders which have different symptoms. Generally, they are neuromuscular disorders characterized by muscle weakness developing in young adults. Hereditary inclusion body myopathies comprise both autosomal recessive and autosomal dominant muscle disorders that have a variable expression (phenotype) in individuals, but all share similar structural features in the muscles.
The most useful information for accurate diagnosis is the symptoms and weakness pattern. If the quadriceps are spared but the hamstrings and iliopsoas are severely affected in a person between ages of 20 - 40, it is very likely
HIBM
will be at the top of the differential diagnosis. The doctor may order any or all of the following tests to ascertain if a person has IBM2:
HIBMs are a group of muscle wasting disorders, which are uncommon in the general world population. One autosomal recessive form of
HIBM
is known as IBM2 or GNE myopathy, which is a common genetic disorder amongst people of Iranian Jewish descent. IBM2 has also been identified in other minorities throughout the world, including people of Asian (Japanese and others), European, and South American origin, as well as Muslim people in the Middle Eastern, Palestinian, and Iranian origin. In Japan and many East Asian countries, this disorder is known as Distal Myopathy with Rimmed Vacuoles (DMRV).