SynonymsBot
Synonyms for hjurp or Related words with hjurp
topk
cenpf
stratifin
zwint
baalc
anln
inhbb
calr
cxadr
uqcrh
wdrpuh
parvb
cenpa
nnat
nfyb
nptxr
ptgdr
wwox
troap
zwilch
rybp
gldc
podxl
htpap
uqcrb
fanci
rkip
mlana
tagln
recql
fkbpl
pdgfc
myof
polq
rerg
ncapg
amfr
ncaph
nfkbia
ywhae
tpte
cflar
rfxank
frzb
prosc
aurkb
mtdh
ptprk
procr
pdgfrl
Examples of "hjurp"
Holliday junction recognition protein is a protein in humans that is encoded by the
HJURP
gene.
Replenishment of CENPA every cycle, which is important for reestablishing centromere identity, is carried out by
HJURP
(Holliday Junction Recognition Protein), or Scm3 in fungi and CAL1 in "Drosophila". Tethering
HJURP
to a non-centromeric locus can give rise to a neocentromere, even after the disassociation of
HJURP
. Interestingly, there seems to be a co-evolutionary relationship between the "Drosophila" chaperone CAL1 and CENPA which accounts for species incompatibility—this is discussed more below.
What has been conserved, or appears to have been? Nearly all eukaryotic organisms, apart from budding yeasts ("Saccharomyces cerevisiae") have satellite DNA in their normal centromeres. Yeast, "Drosophila" and mammals all have heterochromatin flanking their centromeres. Interestingly, although the vertebrate chaperone
HJURP
and the yeast chaperone Scm3 have diverged, their N-terminal domains show striking conservation. On the other hand, frogs and chickens have domains in their chaperones that are not at all shared with that of yeast. Hence, further research into the mechanistic properties of these chaperones may potentially reveal how they help determine where and what type of centromere and neocentromere form.