Synonyms for ptgds or Related words with ptgds

ldhc              cebpd              ptprj              sqle              ptprm              plaur              grina              ptprd              hpgd              pfkp              ptpro              vcan              cubn              aldoa              prkaca              ptgdr              rragd              flnb              cflar              inhba              tagln              ptprn              postn              tnxb              cadps              frzb              tpbg              ptprk              anpep              ehhadh              pdxk              agrn              ptprg              agtrap              rabif              ptprc              nfkbie              ctsz              strbp              ncstn              amfr              lpxn              ptrf              narfl              arhgdia              gabrq              glul              ptpre              ywhae              blvrb             



Examples of "ptgds"
Prostaglandin-H2 D-isomerase (PTGDS) is an enzyme that in humans is encoded by the "PTGDS" gene.
OPCs synthesize the neuromodulatory factors prostaglandin D2 synthase (PTGDS) and neuronal pentraxin 2 (Nptx2). This is mediated by the protein NG2, whose intracellular domain can be cleaved by the γ-secretase and translocated to the nucleus.
Prostaglandin D synthase is used clinically as a diagnostic marker for liquorrhea, that is, to check whether fluid leaking from the nose or ear contains cerebrospinal fluid. This is important in the assessment of head trauma severity. In a medical context, the older term "β-trace protein" is frequently used to refer to PTGDS.
In cells, COX-1 and COX-2 metabolize arachidonic acid to PGH2 which is then converted to PGE2 by any one of three isozymes, PTGES, PTGES2, and PTGES3 or, alternatively, to PGD2 by either of two enzymes, a glutathione-independent synthase termed lipocalin-type Prostaglandin D2 synthase (PTGDS or L-PGDS) and a glutathione-dependent hematopoietic-type H-PGDS or PTGDS2; the COX's also metabolizes dihomo-gamma-linolenic acid to PGH1 which is metabolized by one of the three PTGES isomzymes to PGE1 (see eicosanoid#Prostanoid pathways). PGE2, PGE1, and PGD2 undergo a dehydration reaction PGA2, PGA1, and PGJ2, respectively. PGD2 conversions form the most studied cyclopentenone PGs. These conversions are as follows:
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH) to prostaglandin D2 (PGD). PGD functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice over-expressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Furthermore, PTGDS and its product PGD are elevated in the bald-scalp areas of men with male pattern baldness (androgenetic alopecia).