Synonyms for tcrs or Related words with tcrs

tcr              scfvs              nanobodies              fcrs              muteins              bcrs              btla              epitopes              apcs              ctls              kir              allotypes              autoantigens              vhhs              kirs              fabs              meganucleases              tlrs              sdabs              iggs              sirp              dabs              sctcr              egfrviii              ldcam              heterodimeric              vhh              chimeras              somatically              zfps              ectodomains              gitr              heteromeric              mesothelin              superantigens              glycoforms              mabs              superantigen              gpcrs              gpvi              pilr              bcma              heterodimers              sctcrs              fcr              fhbp              taas              fgfrs              autoreactive              allotype             



Examples of "tcrs"
After the Adria testing session, the Balance of Performance was issued: The Audi RS3 LMS TCRs were given a +45 kg from the minimum weight of 1285 kg, while the Opel Astra TCRs were given +40 kg, the SEAT León TCRs and Honda Civic TCRs were given +30 kg, the Volkswagen Golf GTI TCRs were given +10 kg and the Alfa Romeo Giulietta TCRs were given -20 kg. Both the Volkswagen Golf GTI TCRs and Alfa Romeo Giulietta TCRs were given a -10mm in ride height, running at 70mm from the minimum 80mm in ride height.
After the Valencia testing session, the Balance of Performance was issued: SEAT León TCRs, Honda Civic TCRs and Volkswagen Golf GTI TCRs were given a +30 kg from the minimum weight of 1285 kg, while Subaru Impreza STi TCR received a -20 kg bonus. No changes for Opel Astra TCRs, Alfa Romeo Giulietta TCRs and SEAT León Cup Racers.
In addition, the Balance of Performance was reviewed for this round: Volkswagen Golf GTI TCRs received a -30 kg bonus, while Opel Astra TCRs and Alfa Romeo Giulietta TCRs were given a -20 kg bonus.
Another Tamalpa institution is the Tamalpa Club Racing Series (TCRS), founded in 1983 as a series of low-key cross country running events. TCRS races are held every month except June (in honor of the Dipsea) and December (in deference to Tamalpa Christmas Party hangovers). The TCRS courses are a combination of various traditional courses in Marin County selected each year by the club's race directors.
TCRs are molecules found on the surface of T lymphocytes (or T cells) and play various roles in the immune system. TCRs are often cited as aiding in recognising foreign antigens being presented by cells which have been infected by viruses or intracellular bacteria. Immunocore has developed a line of biologic medicines by combining engineered, cancer-recognizing TCRs with immune activating complexes, which, in theory, creates a drug that directs the immune system to kill cancer cells. These drugs are commonly referred to as immune-mobilizing monoclonal TCRs against cancer (ImmTACs).
TCRs have two parts, usually an alpha and a beta chain. (Some TCRs have a gamma and a delta chain.) Hematopoietic stem cells in the bone marrow migrate into the thymus, where they undergo VDJ recombination of their beta-chain TCR DNA to form a developmental form of the TCR protein, known as pre-TCR. If that rearrangement is successful, the cells then rearrange their alpha-chain TCR DNA to create a functional alpha-beta TCR complex. This highly-variable genetic rearrangement product in the TCR genes helps create millions of different T cells with different TCRs, helping the body's immune system respond to virtually any protein of an invader. The vast majority of T cells express alpha-beta TCRs (αβ T cells), but some T cells in epithelial tissues (like the gut) express gamma-delta TCRs (γδ T cells), which recognize non-protein antigens.
For operational and content qualitative reasons, not more than two television channels are managed from one TCR. Channels with live content and production switching requirements like sports channels have their own dedicated TCRs. A television station may have several TCRs depending on the number of channels they broadcast.
The interaction between TCRs and peptide-MHC complex is significant in maintaining the immune system against foreign antigens. MHC restriction allows TCRs to detect host cells that are infected by pathogens, contains non-self proteins or bears foreign DNA. However, MHC restriction is also responsible for chronic autoimmune diseases and hypersensitivity.
The Germline hypothesis suggests that the ability to bind to MHC is intrinsic and encoded within the germline DNA that are coding for TCRs. This is because of evolutionary pressure selects for TCRs that are capable of binding to MHC and selects against those that are not capable of binding to MHC. Since the emergence of TCR and MHC ~500 million years ago, there is ample opportunity for TCR and MHC to coevolve to recognize each other. Therefore, it is proposed that evolutionary pressure would lead to conserved amino acid sequences at regions of contact with MHCs on TCRs.
As at October 2016, with more than 80 outlets in South East Asia, TCRS is currently the largest chicken rice restaurant chain in the world.
Immunocore is a privately owned British clinical-stage biotechnology company, based in Oxfordshire, which researches and develops cancer treatments using T-cell receptors (TCRs).
The service is open to third-party developers, but they must be able to meet certain Technical Certification Requirements (TCRs), which include (but are not limited to): game ratings, total number of Gamerscore points, content, game profiles, and Live connectivity. Games for Windows – Live games must also meet standard Games for Windows (games that do not have Live support) TCRs. The same developer support infrastructure is available as with the Xbox 360. Assistance to developers is provided through the Microsoft XNA Developer Connection.
The Chicken Rice Shop (TCRS) is a chicken rice fast-food restaurant and Halal family restaurant chain in Malaysia. The chain is operated by TCR Restaurants Sdn Bhd, a company incorporated in Malaysia, which was established in June 2000.
Each T cell expresses clonal TCRs which recognize specific peptide/MHC complex during physical contact between T cell and antigen-presenting cell-APC (MHC class II) or any other cell type (MHC class I)
Supporting this argument, genetically modified T cells without CD4 and CD8 co-receptors express MHC-independent TCRs. It follows that MHC restriction is imposed by CD4 and CD8 co-receptors during positive selection of T cell selection.
The extensive structural diversity of Vδ1 and Vδ3 TCRs and the existence of Vδ1 clones reactive against MHC, MHC-like, or non-MHC molecules suggest recognition of a highly diverse and heterogeneous set of antigens by non-Vδ2 cells, although cognate interactions between non-Vδ2 TCRs and any of these antigens have not been shown yet. MHC class-I-chain-related gene A (MICA) has also been proposed as an important tumor antigen recognized by Vδ1 T cells. However, the very low affinity of MICA–Vδ1 TCR interactions estimated by surface plasmon resonance analyses raises doubts about the functional relevance of MICA or MHC class-I-chain-related gene B (MICB) recognition by Vδ1 TCRs.
The TCRs of T cells recognize linear peptide antigens only if coupled with a MHC molecule. In other words, the ligands of TCRs are specific peptide-MHC complexes. MHC restriction is particularly important for self-tolerance, which makes sure that our immune system do not target ourselves. When primary lymphocytes are developing and differentiating in the thymus or bone marrow, T cells die by apoptosis if they express high affinity for self-antigens presented by an MHC molecule or express too low an affinity for self MHC.
The material used in the detector must demonstrate large changes in resistance as a result of minute changes in temperature. As the material is heated, due to the incoming infrared radiation, the resistance of the material decreases. This is related to the material's temperature coefficient of resistance (TCR) specifically its negative temperature coefficient. Industry currently manufactures microbolometers that contain materials with TCRs near -2%/K. Although many materials exist that have far higher TCRs, there are several other factors that need to be taken into consideration when producing optimized microbolometers.
In immunology, an idiotype is a shared characteristic between a group of immunoglobulin or T cell receptor (TCR) molecules based upon the antigen binding specificity and therefore structure of their variable region. The variable region of antigen receptors of T cells (TCRs) and B cells (immunoglobulins) contain complementarity determining regions (CDRs) with unique amino acid sequences. They define the surface and properties of the variable region, determining the antigen specificity and therefore the idiotope of the molecule. Immunoglobulins or TCRs with a shared idiotope are the same idiotype. Antibody idiotype is determined by:
During positive selection, co-receptors CD4 and CD8 initiate a signaling cascade following MHC binding. This involves the recruitment of Lck, a tyrosine kinase essential for T cell maturation that is associated with the cytoplasmic tail of the CD4 or CD8 co-receptors. Selection model argues that Lck is directed to TCRs by co-receptors CD4 and CD8 when they recognize MHC molecules. Since TCRs interact better with Lck when they are binding to the MHC molecules that are binding to the co-receptors in a ternary complex, T cells that can interact with MHCs bound to by the co-receptors can activate the Lck kinase and receive a survival signal.